梁瑞政教授

梁瑞政，男，教授，博导，2009-2015年北京化工大学硕博连读，导师为段雪院士(中国科学院)，期间被国家留学基金委委派到英国牛津大学留学。2015年以人才引进在北京化工大学留校任教，2021年破格晋升教授，博导。近年来开展层状双金属氢氧化物(LDHs)生物医用材料的基础和应用基础研究，取得如下成果：1）创制了系列近红外I–II区激发、高单态氧产率的LDHs基光敏剂材料，实现了高效光动力肿瘤治疗；进一步将LDHs材料拓展到化学动力治疗和超声动力治疗领域。2）构建了系列高性能镁基LDHs生物活性骨修复材料，以应用为导向，开展LDHs基抗骨关节炎注射液的应用研究和临床前研究。以第一作者或通讯作者在Nat. Commun. (2)、Adv. Mater. (5)、Chem. Soc. Rev.、ACS Nano、Adv. Funct. Mater.、Adv. Sci.、Sci. Bull.等刊物发表SCI论文60余篇。8篇论文入选ESI高被引TOP 1%论文，2篇入选热点论文。研究工作被各类学术网站亮点报道30余次。受邀担任Exploration、中国化学快报和物理化学学报青年编委，Applied Sciences编委，Frontiers in Molecular Biosciences客座主编。参编中文专著1部。申请国家发明专利18件，获得授权14件。荣获北京市科技进步二等奖，北京化工大学青年英才百人计划（首批）等荣誉。

8篇代表性文章：（*代表通讯作者，#代表共同一作）

1. T. Hu, Z. Gu, G. R. Williams, M. Strimaite, J. Zha, Z. Zhou, X. Zhang,* C. Tan,* R. Liang,* Layered double hydroxide-based nanomaterials for biomedical applications, Chem. Soc. Rev., 2022, 51, 6126−6176.

2. W. Shen,# T. Hu,# X. Liu, J. Zha, F. Meng, Z. Wu, Z. Cui, Y. Yang, H. Li, Q. Zhang, L. Gu, R. Liang,* C. Tan,* Defect Engineering of Layered Double Hydroxide Nanosheets as Inorganic Photosensitizers for NIR-III Photodynamic Cancer Therapy, Nat. Commun., 2022, 13, 3384.

3. R. Gao,# X. Mei,# D. Yan,* R. Liang,* M. Wei, Nano-photosensitizer based on layered double hydroxide and isophthalic acid for singlet oxygenation and photodynamic therapy, Nat. Commun., 2018, 9, 2798.

4. T. Hu,# W. Shen,# F. Meng,# S. Yang, S. Yu, H. Li, Q. Zhang, L. Gu,* C. Tan,* R. Liang,* Boosting the sonodynamic cancer therapy performance of 2D layered double hydroxide nanosheet-based sonosensitizers via crystalline-to-amorphous phase transformation, Adv. Mater., 2023, 35, 2209692.

5. Y. Yang,# T. Hu,# Y. Bian,# F. Meng, S. Yu, H. Li, Q. Zhang, L. Gu, X. Weng,* C. Tan,* R. Liang,* Coupling probiotics with 2D CoCuMo-LDH nanosheets as tumor microenvironment-responsive platform for precise NIR-II photodynamic therapy, Adv. Mater., 2023, 35, 2211205.

6. Z. Lv,# T. Hu,# Y. Bian,# G. Wang, Z. Wu, H. Li, X. Liu, S. Yang, C. Tan,* R. Liang,* X. Weng*, A MgFe-LDH Nanosheet-Incorporated Smart Thermo-Responsive Hydrogel with Controllable Growth Factor Releasing Capability for Bone Regeneration, Adv. Mater., 2023,35, 2206545.

7. W. Liu, S. Xu, S. Guan, R. Liang,* M. Wei,* D. G. Evans, X. Duan, Confined synthesis of carbon nitride in a layered host matrix with unprecedented solid-state quantum yield and stability, Adv. Mater., 2018, 30, 1704376.

8. L. Peng, X. Mei, J. He, J. Xu, W. Zhang,* R. Liang,* M. Wei,* D. G. Evans, X. Duan, Monolayer Nanosheets with an Extremely High Drug Loading toward Controlled Delivery  and Cancer Theranostics, Adv. Mater., 2018, 30, 1707389.